Could a blood pressure drug clear brain fog in the ICU?

NCT ID NCT04742673

First seen Feb 05, 2026 · Last updated Apr 28, 2026 · Updated 17 times

Summary

This study tested whether a medicine called guanfacine, given through an IV, can help reduce confusion and improve thinking in very sick patients in the intensive care unit (ICU). 46 adults on breathing machines or with shock took part. The goal was to see if the drug could increase days without delirium or coma.

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Contacts and locations

Locations

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37212, United States

Conditions

Explore the condition pages connected to this study.