Could a blood pressure drug boost brain power in depression?

NCT ID NCT06408246

First seen Jan 11, 2026 · Last updated Jun 04, 2026 · Updated 23 times

Summary

This study tests how guanfacine, a medication typically used for blood pressure, affects brain networks and thinking problems in people with depression. Researchers will enroll 162 adults aged 18-60 who are currently experiencing a major depressive episode. The goal is to see if the drug can help relieve depressive symptoms and improve daily functioning and quality of life.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Stanford Psychiatry and Behavioral Sciences Department

    RECRUITING

    Palo Alto, California, 94305, United States

  • University of Illinois at Chicago

    RECRUITING

    Chicago, Illinois, 60607, United States

    Contact

    Contact

Conditions

Explore the condition pages connected to this study.