Can a blood pressure drug lift depression? new trial aims to find out

NCT ID NCT06408246

Recruiting now Symptom relief Sponsor: Stanford University Source: ClinicalTrials.gov ↗

First seen Jan 11, 2026 · Last updated Apr 30, 2026 · Updated 17 times

Summary

This study tests whether guanfacine, a medication typically used for blood pressure, can improve brain function and reduce depressive symptoms. Researchers will enroll 162 adults with depression to see if the drug helps with thinking problems and leads to remission. The goal is to understand how guanfacine affects brain networks and whether it can ease depression.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Stanford Psychiatry and Behavioral Sciences Department
RECRUITING

Palo Alto, California, 94305, United States
University of Illinois at Chicago
RECRUITING

Chicago, Illinois, 60607, United States

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Conditions

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DEPRESSION