Could a blood pressure drug clear brain fog in the ICU?

NCT ID NCT04742673

First seen Feb 05, 2026 · Last updated Jun 10, 2026 · Updated 32 times

Summary

This study looked at whether giving a drug called guanfacine through an IV can help reduce delirium and improve thinking in very sick patients in the intensive care unit (ICU). The trial included 46 adults who needed breathing or blood pressure support. Researchers measured how many days patients were free of delirium or coma, and how well their brains worked after leaving the hospital.

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Contacts and locations

Locations

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37212, United States

Conditions

Explore the condition pages connected to this study.