Experimental cell therapy targets kidney disease

NCT ID NCT07389499

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial is testing a new cell therapy called GT719 for several immune-mediated kidney diseases, including IgA nephropathy and membranous nephropathy. The therapy uses specially engineered immune cells to target and potentially control the disease. The study will enroll 30 adults to first assess safety and find the right dose, then expand to evaluate effectiveness more closely.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

GT719 universal cell injection (CD19-targeted iNKT cells)

What this could lead to

If it works, this could point toward a new treatment option for certain immune-mediated kidney diseases, potentially reducing the need for long-term immunosuppression.

What could go wrong

This is a very early (Phase 1) trial with only 30 participants, so safety and effectiveness are not yet proven. Cell therapies can have serious side effects, and the results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anti-neutrophil cytoplasmic antibody-associated vasculitis granulomatosis with polyangiitis IgA glomerulonephritis membranous glomerulonephritis non-amyloid monoclonal immunoglobulin deposition disease pauci-immune glomerulonephritis with ANCA proliferative glomerulonephritis steroid-resistant nephrotic syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Zhongshan Hospital Affiliated to Fudan University

    Shanghai, Shanghai Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact