New ulcerative colitis drug takes first step in human testing

NCT ID NCT06681181

First seen Oct 31, 2025 · Last updated May 14, 2026 · Updated 21 times

Summary

This study is the first time GSK4528287, a drug for inflammatory bowel diseases like ulcerative colitis, is being given to humans. It involves 48 healthy volunteers who receive a single dose to check for side effects, measure drug levels in the blood, and see how the drug works in the body. The dose is increased gradually in different groups to find a safe range.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • GSK Investigational Site

    Cambridge, CB2 0GG, United Kingdom

Conditions

Explore the condition pages connected to this study.