New drug combo targets tough tumors
NCT ID NCT05840224
First seen Jun 27, 2026 · Last updated Jul 28, 2026 · Updated 2 times
Summary
This early-stage study tests a new drug called GS-4528, given alone or with another cancer drug (anti-PD-1), in adults with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety and find the best dose. About 182 participants will take part.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Asan Medical Center
Seoul, 05505, South Korea
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Chang Gung Memorial Hospital Linkuo Branch of the Chang Gung Medical Foundation
Taoyuan, 333, Taiwan
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Clinica Universidad de Navarra- Unidad Central de Ensayos Clinicos
Pamplona, 31008, Spain
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Hospital Universitari Vall D'Hebron- Oncology Service
Barcelona, 08035, Spain
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NEXT Oncology-Hospital Quironsalud Barcelona - Unidad de Ensayos Fase 1
Barcelona, 08023, Spain
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National Taiwan University Hospital
Taipei, 100229, Taiwan
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START MADRID_HM Sanchinarro-CIOCC-Unidad de Ensayos Fases I
Madrid, 28050, Spain
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START MADRID_Hospital Universitario Fundacion Jimenez Diaz - Unidad de Ensayos Fases I
Madrid, 28040, Spain
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Samsung Medical Center
Seoul, 06351, South Korea
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Severance Hospital, Yonsei University Health Systems
Seoul, 06273, South Korea
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St Bartholomew's Hospital
London, E1 1FR, United Kingdom
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Taichung Veterans General Hospital
Taichung, 40705, Taiwan
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The Ottawa Hospital
Ottawa, K1H 8L6, Canada
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The Royal Marsden NHS Foundation Trust
Sutton, SM2 5PT, United Kingdom
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The University of Washington/FHCC
Seattle, Washington, 98109, United States
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University Health Network, Princess Margaret Cancer Centre
Toronto, M5G 1Z5, Canada
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