Grape seed mouthrinse takes on plaque in new trial
NCT ID NCT00838266
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a mouthrinse made with red grape seed extract and a fluoride compound can reduce dental plaque. Fifty healthy volunteers used the rinse three times a day for four days without brushing. The trial was double-blind and cross-over, meaning each person tried both the active rinse and a placebo. Researchers measured plaque buildup and checked for side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- mouthrinse containing red grape seed extract and nicomethanol fluorhydrate
- What this could lead to
- If it works, this could offer a new option for controlling dental plaque between brushings.
- What could go wrong
- This is a small, short-term trial (4 days) and may not reflect real-world use. The effect may be small or not better than a placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU de Bordeaux - Hôpital ST André - 1 rue Jean Burguet
Bordeaux, 33075, France
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