New hope for myeloma: experimental drug takes on standard combo

NCT ID NCT07452198

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial is testing a new drug called GR1803 against a standard three-drug combination (daratumumab, pomalidomide, and dexamethasone) in people with multiple myeloma that has come back after 1 to 3 prior treatments. About 358 participants will be randomly assigned to receive either GR1803 or the standard combo. The main goal is to see which treatment keeps the cancer from growing longer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

GR1803 injection (a drug given intravenously)

What this could lead to

If GR1803 works better than the current standard, it could offer a new treatment option for people with multiple myeloma that has come back after earlier therapies.

What could go wrong

This is an early Phase 3 trial, so results are not yet known. The new drug may not be more effective or could have unexpected side effects compared to the existing combination.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

plasma cell myeloma refractory plasma cell neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences

    RECRUITING

    Tianjin, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••