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New hope for stubborn gout: experimental drug PRX-115 enters phase 2 trial

NCT ID NCT07280156

Recruiting now Disease control Sponsor: Protalix Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new medicine called PRX-115, given through a vein, to see if it can lower uric acid levels in adults with gout who haven't improved with standard pills. About 150 participants will receive either PRX-115 (with or without methotrexate) or a placebo over 24 weeks. The main goal is to find the best dose and check if the drug safely reduces uric acid below the target level.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gout Hyperuricemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GOUT

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Accel Research Sites - Deland Clinical Research Unit

    RECRUITING

    DeLand, Florida, 32720, United States

  • Aleksandre Aladashvili Clinic LLC, Georgia

    RECRUITING

    Tbilisi, 0102, Georgia

  • Altoona Center for Clinical Research

    RECRUITING

    Duncansville, Pennsylvania, 16635, United States

  • Applied Research Center of Arkansas

    RECRUITING

    Little Rock, Arkansas, 72205, United States

  • Barzilai MC, Israel

    RECRUITING

    Ashkelon, 7830604, Israel

  • Bioclinical Research Alliance, Inc

    RECRUITING

    Miami, Florida, 33155, United States

  • Centricity Research - Columbus Georgia Multispecialty

    RECRUITING

    Columbus, Georgia, 31904, United States

  • Clinical Research of West Florida, Inc.

    RECRUITING

    Clearwater, Florida, 33765, United States

  • Clinical Research of West Florida, Inc.

    RECRUITING

    Tampa, Florida, 33606, United States

  • Combined Research Orlando Phase I-IV

    RECRUITING

    Orlando, Florida, 32897, United States

  • Conquest Research - Lake Nona

    RECRUITING

    Orlando, Florida, 32832, United States

  • D&H National Research Centers (North Miami)

    RECRUITING

    Miami, Florida, 33169, United States

  • Georgian-Dutch Hospital, Georgia

    RECRUITING

    Tbilisi, 0172, Georgia

  • HaEmek MC, Israel

    RECRUITING

    Afula, 1834111, Israel

  • ICR Sites East

    RECRUITING

    Doral, Florida, 33125, United States

  • LTD First Medical Center, Georgia

    RECRUITING

    Tbilisi, 0180, Georgia

  • Mediclub Georgia

    RECRUITING

    Tbilisi, 0160, Georgia

  • Meir MC, Israel

    RECRUITING

    Kfar Saba, 4438164, Israel

  • Mt. Olympus Medical Research, LLC - Sugar Land

    RECRUITING

    Sugar Land, Texas, 77479, United States

  • New Horizons Research

    RECRUITING

    Palmetto Bay, Florida, 33176, United States

  • Pioneer Research Solutions Inc

    RECRUITING

    Houston, Texas, 77099, United States

  • Quest Research Institute

    RECRUITING

    Farmington Hills, Michigan, 48334, United States

  • Qway Research

    RECRUITING

    Hialeah, Florida, 33010, United States

  • Tbilisi Heart and Vascular Clinic Ltd , Georgia

    RECRUITING

    Tbilisi, 0159, Georgia

  • Tbilisi Institute of Medicine, Georgia

    RECRUITING

    Tbilisi, 0160, Georgia

  • Triwest Research Associates Llc

    RECRUITING

    El Cajon, California, 91910, United States

  • Well Pharma Medical Research Group

    RECRUITING

    Miami, Florida, 33173, United States

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