New hope for brain lymphoma: experimental antibody targets Hard-to-Treat cancers

NCT ID NCT05485753

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 25 times

Summary

This study tests an experimental drug called GNC-038 in people with central nervous system lymphoma that has come back or not responded to treatment. The drug is a special antibody designed to attack cancer cells in the brain and spinal cord. The main goals are to check safety, find the best dose, and see if it shrinks tumors. About 7 adults will take part.

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Contacts and locations

Locations

  • Beijing GoBroad Boren Hospital

    Beijing, Beijing Municipality, China

  • Beijing Tiantan Hospital, Capital Medical University

    Beijing, Beijing Municipality, 100070, China

  • Guangdong Provincial People's Hospital

    Guangzhou, Guangdong, China

  • The First Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, China

Conditions

Explore the condition pages connected to this study.