Can a daily pill slow aging? new trial tests GLYLO supplement in postmenopausal women

NCT ID NCT06813261

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This pilot study tests whether a dietary supplement called GLYLO can lower harmful compounds called AGEs in overweight or obese postmenopausal women aged 45-65. Participants take either GLYLO or a placebo for 24 weeks, and researchers measure changes in AGEs, insulin resistance, and physical/cognitive function. The goal is to see if this supplement can improve metabolic health and slow age-related decline.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

GLYLO (a combination of benfotiamine, vitamin B6, nicotinamide, alpha lipoic acid, and piperine)

What this could lead to

If it works, this could point toward a simple supplement to slow some aspects of aging and improve metabolic health in postmenopausal women.

What could go wrong

This is a very small, early pilot trial with only 30 participants. The supplement may not reduce AGEs or improve health outcomes, and results may not apply to all women.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metabolic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Buck Institute for Research on Aging

    RECRUITING

    Novato, California, 94945, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••