Brain fuel mystery: could glucagon be the key?

NCT ID NCT07350512

Not yet recruiting Knowledge-focused Sponsor: Nicolai Jacob Wewer Albrechtsen Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study will test how the hormone glucagon affects brain function and sugar metabolism in 15 healthy adults. Participants receive an intravenous infusion of alanine, which triggers glucagon release, while researchers measure changes in blood sugar and other markers. The goal is to understand glucagon's role in the brain, which could lead to new insights into metabolic and cognitive health.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: alanine
What this could lead to: If successful, this could reveal how glucagon influences brain energy use and thinking, possibly pointing to new ways to treat metabolic or cognitive disorders.
What could go wrong: This is a very early, small pilot study in healthy people, so results may not apply to patients. It only looks at short-term effects, not long-term benefits or risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

glucose metabolism disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLUCAGON GLUCOSE METABOLISM

Contacts and locations

Locations

Department of Clinical Biochemistry, Copenhagen University Hospital - Bispebjerg and Frederiksberg

Copenhagen, Denmark

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