New pill targets brain Cancer's weakness in early human trial

NCT ID NCT07464925

Summary

This is a first-in-human study to find a safe dose of an experimental oral drug called GLIX1 for adults with aggressive brain tumors (high-grade glioma or glioblastoma) that have returned or worsened after standard treatments. The main goal is to check the drug's safety and side effects in about 30 participants, who will take daily capsules. Researchers will also look for early signs that the drug might help control the cancer by causing DNA damage specifically in tumor cells.

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Contacts and locations

Locations

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • NYU Langone Health

    New York, New York, 10016, United States

  • Northwestern Medicine

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.