New hope for aggressive brain cancer: combo therapy trial launches

NCT ID NCT06061809

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 31 times

Summary

This study tests a combination of drugs (nogapendekin alfa inbakicept, bevacizumab, and immune cells called PD-L1 t-haNK) with or without tumor treatment fields (a device that uses electric fields to disrupt cancer growth) in people whose glioblastoma has come back or worsened. The goal is to see if these combinations are safe and can help control the tumor. About 34 adults will take part, receiving treatment for up to 76 or 80 weeks depending on the phase.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chan Soon-Shiong Institute for Medicine (CSSIFM)

    NOT_YET_RECRUITING

    El Segundo, California, 90245, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hoag Memorial Hospital Presbyterian

    RECRUITING

    Newport Beach, California, 92663, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

  • Providence Medical Foundation

    RECRUITING

    Fullerton, California, 92835, United States

    Contact Phone: •••-•••-••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vanderbilt-Ingram Cancer Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.