New brain cancer combo shows early safety signal

NCT ID NCT03535350

Summary

This early-stage study is testing whether adding the drug ibrutinib to standard radiation and chemotherapy (temozolomide) is safe for people newly diagnosed with glioblastoma, an aggressive brain cancer. Researchers want to find the highest safe dose of ibrutinib and see if radiation helps deliver more of the drug to the brain tumor. The study enrolled 36 participants with two different genetic types of glioblastoma.

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Contacts and locations

Locations

  • Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center

    Cleveland, Ohio, 44195, United States

Conditions

Explore the condition pages connected to this study.