Brain cancer fight: triple attack with drug, diet, and diabetes pill

NCT ID NCT05183204

First seen Jan 05, 2026 · Last updated Apr 04, 2026 · Updated 15 times

Summary

This study is testing a three-part treatment for glioblastoma, a fast-growing brain cancer. It combines a new drug called paxalisib, the diabetes medication metformin, and a strict high-fat, low-carb ketogenic diet. The goal is to see if this combination is safe and can help control the cancer by potentially starving tumor cells and blocking their growth signals.

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Contacts and locations

Locations

  • Weill Cornell Medicine

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.