New Two-Drug attack on deadly brain cancer begins human testing

NCT ID NCT04656535

Summary

This early-phase study is testing the safety of a new two-drug combination (domvanalimab and zimberelimab) for adults with glioblastoma that has returned after initial treatment. The trial will enroll 46 patients to see how well the drugs are tolerated and to study their effects on the tumor and immune system. Some participants will receive the drugs before a planned surgery to allow researchers to directly analyze the treatment's impact on the cancer.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • University of California San Francisco

    San Francisco, California, 94143, United States

  • Yale University

    New Haven, Connecticut, 06519, United States

Conditions

Explore the condition pages connected to this study.