Scientists launch major effort to unlock secrets of rare stomach cancer

NCT ID NCT04557969

Recruiting now Knowledge-focused Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Aug 14, 2026 · Updated 6 times

Summary

This study follows 400 people aged 6 and older who have a rare stomach cancer called GIST. Researchers will collect tumor tissue during surgery and study it in the lab to learn more about the disease. Participants are monitored every 6 to 12 months for up to 10 years before surgery and 5 years after. The goal is to better understand GIST and support future research, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could help scientists understand GISTs better and point toward new treatments for this rare cancer.
What could go wrong: This is an observational study, not a treatment trial. It collects data and tissue but does not test a new drug or therapy, so direct patient benefits are unlikely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gastric cancer gastric neoplasm gastrointestinal stromal tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GASTRIC CANCER GASTRIC NEOPLASM GASTROINTESTINAL STROMAL NEOPLASM GASTROINTESTINAL STROMAL SARCOMA GASTROINTESTINAL STROMAL TUMOR (GIST)

Contacts and locations

Locations

National Institutes of Health Clinical Center
RECRUITING

Bethesda, Maryland, 20892, United States

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