Ginseng vs. fatigue: major trial tests natural remedy for cancer patients

NCT ID NCT06395441

Recruiting now Symptom relief Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase III trial tests whether American ginseng can reduce fatigue in 160 cancer patients. Fatigue is a common and tough side effect of cancer and its treatment. Participants will take either ginseng or a placebo, and researchers will measure changes in fatigue levels over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: American ginseng (dietary supplement)
What this could lead to: If it works, this could provide a natural option to ease cancer-related fatigue, improving quality of life for many patients.
What could go wrong: This is a large Phase III trial, but fatigue is subjective and the placebo effect is strong. Ginseng may not outperform placebo, and results may not apply to all cancer types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer hematopoietic and lymphoid system neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM MALIGNANT SOLID NEOPLASM

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Essentia Health Cancer Center
RECRUITING

Duluth, Minnesota, 55805, United States

Contact Email: •••••@•••••
Essentia Health Deer River Clinic
RECRUITING

Deer River, Minnesota, 56636, United States

Contact Email: •••••@•••••
Essentia Health Fosston
RECRUITING

Fosston, Minnesota, 56542, United States

Contact Email: •••••@•••••
Essentia Health Hibbing Clinic
RECRUITING

Hibbing, Minnesota, 55746, United States

Contact Email: •••••@•••••
Essentia Health Saint Joseph's Medical Center
RECRUITING

Brainerd, Minnesota, 56401, United States

Contact Email: •••••@•••••
Essentia Health Sandstone
RECRUITING

Sandstone, Minnesota, 55072, United States

Contact Email: •••••@•••••
Essentia Health St. Mary's Detroit Lakes Clinic
RECRUITING

Detroit Lakes, Minnesota, 56501, United States

Contact Email: •••••@•••••
Essentia Health Virginia Clinic
RECRUITING

Virginia, Minnesota, 55792, United States

Contact Email: •••••@•••••
MMCORC CentraCare Monticello Cancer Center
COMPLETED

Monticello, Minnesota, 55362, United States
Mayo Clinic Health System in Albert Lea
RECRUITING

Albert Lea, Minnesota, 56007, United States

Contact Email: •••••@•••••
Mayo Clinic Health System-Mankato
RECRUITING

Mankato, Minnesota, 56001, United States

Contact Email: •••••@•••••
Mayo Clinic in Rochester
RECRUITING

Rochester, Minnesota, 55905, United States

Contact Email: •••••@•••••
Sanford Joe Lueken Cancer Center
RECRUITING

Bemidji, Minnesota, 56601, United States

Contact Email: •••••@•••••
Sanford Thief River Falls Medical Center
RECRUITING

Thief River Falls, Minnesota, 56701, United States

Contact Email: •••••@•••••
Sanford Worthington Medical Center
RECRUITING

Worthington, Minnesota, 56187, United States

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