New COVID-19 vaccine shows promise in early trial
NCT ID NCT04639466
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested a new COVID-19 vaccine called GEO-CM04S1 in 119 healthy adults. The vaccine uses a modified virus to teach the body to fight SARS-CoV-2. Researchers checked for side effects and measured antibody levels to see if the vaccine works. The trial is now complete.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
GEO-CM04S1 (a synthetic MVA-based SARS-CoV-2 vaccine)
What this could lead to
If successful, this vaccine could provide a new option to prevent COVID-19 infection and boost immunity against the virus.
What could go wrong
This is an early-phase trial with only 119 participants, so results may not apply to the general population. The vaccine may not produce strong enough immunity or could have side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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City of Hope Comprehensive Cancer Center
Duarte, California, 91010, United States
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EmVenio Research
Claremont, California, 91711, United States
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Millennium Clinical Trials
Thousand Oaks, California, 91360, United States