Personalized pain pills: gene test may cut opioid risks after hernia repair
NCT ID NCT06565546
First seen Jun 26, 2026 · Last updated Jul 08, 2026 · Updated 3 times
Summary
This study tests whether using a genetic test (CYP2D6) to choose pain medications can improve pain control and quality of life for 100 adults undergoing elective ventral hernia repair. Participants receive either standard pain meds or meds guided by their genetic profile. The goal is to see if this personalized approach is feasible and effective.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- CYP2D6 genotype testing to guide opioid pain medication
- What this could lead to
- If successful, this could lead to personalized pain management that reduces side effects and improves recovery after hernia surgery.
- What could go wrong
- This is a small pilot study (100 people) testing feasibility, not effectiveness. Genetic testing may not improve pain control for everyone.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Florida Jacksonville
Jacksonville, Florida, 32209, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can we predict mesh infections before they happen? a new study aims to find out
- Which hernia repair technique causes less pain? a trial puts two methods Head-to-Head
- Can a robot help heal large hernias faster? a trial puts it to the test
- Can a flap made from the hernia sac itself prevent mesh complications?
- Could a muscle relaxant cut opioid use after hernia surgery?
- Physical therapy after hernia surgery shows promise in small trial