Personalized pain pills: gene test may cut opioid risks after hernia repair

NCT ID NCT06565546

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether using a genetic test (CYP2D6) to choose pain medications can improve pain control and quality of life for 100 adults undergoing elective ventral hernia repair. Participants receive either standard pain meds or meds guided by their genetic profile. The goal is to see if this personalized approach is feasible and effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CYP2D6 genotype testing to guide opioid pain medication

What this could lead to

If successful, this could lead to personalized pain management that reduces side effects and improves recovery after hernia surgery.

What could go wrong

This is a small pilot study (100 people) testing feasibility, not effectiveness. Genetic testing may not improve pain control for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Hernia, Ventral

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Florida Jacksonville

    Jacksonville, Florida, 32209, United States