New balloon treatment could unclog tiny heart arteries without stents

NCT ID NCT07158307

ENROLLING_BY_INVITATION Disease control Sponsor: Genoss Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This study is testing a special balloon coated with a drug (paclitaxel) and natural substances (shellac and vitamin E) to treat small coronary artery disease. The balloon is inflated inside the narrowed artery to deliver the drug and help keep it open. Researchers will follow 3,000 adults for several years to see if this approach reduces heart-related complications like heart attack or the need for repeat procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: paclitaxel-coated balloon catheter with shellac and vitamin E
What this could lead to: If successful, this could provide a safer, effective way to treat small coronary artery disease without permanent implants like stents.
What could go wrong: This is an observational study, not a randomized trial, so results may be less definitive. Risks include vessel injury or incomplete opening.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder coronary microvascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY DISEASE (CAD)

Contacts and locations

Locations

Ulsan University Hospital

Ulsan, 44033, South Korea

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