Tailoring radiation by tumor genes: a tiny step toward smarter lung cancer treatment
NCT ID NCT05873439
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This small, completed study tested whether it is possible to personalize radiation doses for people with stage II or III non-small cell lung cancer based on the genetic profile of their tumor. Three participants received either standard or higher radiation doses depending on a radiosensitivity index from their biopsy. The goal was to see if this approach is feasible and safe, not yet to prove it works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
radiation therapy
What this could lead to
If successful, this approach could lead to more effective radiation dosing for lung cancer, potentially improving tumor control while managing side effects.
What could go wrong
This is a very early feasibility study with only 3 participants, so results may not apply broadly. Higher radiation doses also carry a risk of serious side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Moffitt Cancer Center
Tampa, Florida, 33612, United States