Tailoring radiation by tumor genes: a tiny step toward smarter lung cancer treatment
NCT ID NCT05873439
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This small, completed study tested whether it is possible to personalize radiation doses for people with stage II or III non-small cell lung cancer based on the genetic profile of their tumor. Three participants received either standard or higher radiation doses depending on a radiosensitivity index from their biopsy. The goal was to see if this approach is feasible and safe, not yet to prove it works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- radiation therapy
- What this could lead to
- If successful, this approach could lead to more effective radiation dosing for lung cancer, potentially improving tumor control while managing side effects.
- What could go wrong
- This is a very early feasibility study with only 3 participants, so results may not apply broadly. Higher radiation doses also carry a risk of serious side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Moffitt Cancer Center
Tampa, Florida, 33612, United States
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