Massive gene hunt aims to unlock secrets of blood disorders

NCT ID NCT02720679

Recruiting now Knowledge-focused Sponsor: St. Jude Children's Research Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study collects blood, bone marrow, and other samples along with health information from up to 1,716 people with non-cancerous blood diseases and their family members. Researchers will analyze the participants' genes to find new genetic causes of these conditions and understand why some people get sicker than others. The goal is to build a resource that can lead to better diagnosis and treatment in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could uncover new genetic causes of blood diseases and point toward better ways to diagnose or treat them in the future.
What could go wrong: This is a sample-collection study, not a treatment trial. It may take years to produce meaningful results, and findings may not lead directly to new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

blood coagulation disease Bone Marrow Failure Disorders bone marrow failure syndrome Diamond-Blackfan anemia dyskeratosis congenita erythrocyte disorder Fanconi anemia inherited thrombocytopenia Kostmann syndrome leukocyte disorder myelodysplastic syndrome Myelodysplastic Syndromes myeloproliferative neoplasm severe congenital neutropenia sickle cell disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BLOOD COAGULATION DISORDER BONE MARROW FAILURE SYNDROMES CONGENITAL THROMBOCYTOPENIA DIAMOND-BLACKFAN ANEMIA DYSKERATOSIS CONGENITA ERYTHROCYTE DISORDER FANCONI ANEMIA HEMOSTASIS LEUKOCYTE DISORDER MYELODYSPLASTIC SYNDROMES MYELOPROLIFERATIVE DISEASES SEVERE CONGENITAL NEUTROPENIA SICKLE CELL DISEASE

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

St. Jude Children's Research Hospital
RECRUITING

Memphis, Tennessee, 38105, United States

Contact Email: •••••@•••••

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