Engineered immune cells take on Hard-to-Treat cancers

NCT ID NCT03686124

Recruiting now Disease control Sponsor: Immatics US, Inc. Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 32 times

Summary

This study tests a new treatment for adults with solid tumors that have come back or not responded to standard therapies. The treatment uses a patient's own immune cells that are genetically modified to recognize and attack cancer cells. Some participants will also receive the drug nivolumab. The goal is to find safe doses and see if the treatment can shrink tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Charité Benjamin Franklin - Klinik für Hämatologie und Onkologie
RECRUITING

Berlin, 12203, Germany
Fox Chase Cancer Center
RECRUITING

Philadelphia, Pennsylvania, 19111, United States

Contact

Contact Email: •••••@•••••
Fred Hutchinson Cancer Center
RECRUITING

Seattle, Washington, 98109, United States

Contact Email: •••••@•••••
Klinikum rechts der Isar der Technischen Universität München
RECRUITING

Munich, Bavaria, 81675, Germany
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States

Contact Phone: •••-•••-••••
Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Ohio State University Wexner Medical Center Gynecologic Oncology at Mill Run
RECRUITING

Columbus, Ohio, 43026, United States

Contact Email: •••••@•••••
Stanford Cancer Institute
RECRUITING

Stanford, California, 94305, United States

Contact Email: •••••@•••••
Thomas Jefferson University, Honickman Center
RECRUITING

Philadelphia, Pennsylvania, 19107, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Chicago Medical Center
RECRUITING

Chicago, Illinois, 60637, United States

Contact
University of Colorado, Anschutz Medical Campus
RECRUITING

Aurora, Colorado, 80045, United States

Contact Phone: •••-•••-••••
University of Miami Hospital and Clinics
RECRUITING

Miami, Florida, 33136, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Pennsylvania, Perelamn Center for Advanced Medicine
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

Contact Email: •••••@•••••
University of Pittsburgh Medical Center
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
University of Texas MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Universitätsklinikum Bonn - Medizinische Klinik III
RECRUITING

Bonn, North Rhine-Westphalia, 53127, Germany
Universitätsklinikum C.-G.-Carus Dresden
RECRUITING

Dresden, Saxony, 01307, Germany
Universitätsklinikum Hamburg-Eppendorf
RECRUITING

Hamburg, 20246, Germany
Universitätsklinikum Heidelberg, Nationales Centrum für Tumorerkrankungen (NCT)
RECRUITING

Heidelberg, Baden-Wurttemberg, 69120, Germany
Universitätsklinikum Würzburg
RECRUITING

Würzburg, Bavaria, 97080, Germany
Universitätsmedizin der Johannes Gutenberg-Universität Mainz
RECRUITING

Mainz, Rhineland-Palatinate, 55131, Germany

Conditions

Explore the condition pages connected to this study.

CANCER RECURRENT CANCER RECURRENT CANCER REFRACTORY CANCER SOLID TUMOR, ADULT