New genetic sleuthing could solve mysterious fetal swelling cases
NCT ID NCT03911531
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether whole exome and whole genome sequencing can uncover genetic causes of nonimmune fetal hydrops—a serious condition where fluid builds up in a fetus—when standard tests find nothing. Researchers will analyze DNA from 55 affected fetuses or newborns and their parents. The goal is to improve diagnosis and help families understand risks for future pregnancies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help identify hidden genetic causes of fetal hydrops, improving diagnosis and family counseling for future pregnancies.
What could go wrong
This is a small, early-stage study (55 participants) focused on diagnosis, not treatment. It may not find new causes in all cases, and results may not apply to broader populations.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Thomas Jefferson University
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
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