5,000 hearts, one quest: scientists hunt for hidden genes behind birth defects

NCT ID NCT01192048

Recruiting now Knowledge-focused Sponsor: Nationwide Children's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to find the genetic causes of congenital heart disease, the most common birth defect. Researchers will collect blood samples from 5,000 people with the condition and their family members. By analyzing their DNA, they hope to discover new genes that contribute to heart defects, which could lead to better diagnosis and future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help identify new genes linked to congenital heart disease, improving diagnosis and future treatment targets.
What could go wrong: This is an observational study, not a treatment trial. It may not directly benefit participants, and finding genetic causes does not guarantee new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CONGENITAL HEART DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Congenital Abnormalities congenital heart disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CONGENITAL HEART DISEASE

Contacts and locations

Locations

Nationwide Children's Hospital
RECRUITING

Columbus, Ohio, 43205, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.