Scientists hunt for Eye-Misalignment genes

NCT ID NCT04770519

Recruiting now Knowledge-focused Sponsor: Boston Children's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aims to find genetic variants linked to strabismus (crossed eyes) and nystagmus (involuntary eye movements). Researchers will analyze DNA from families with at least three members who have strabismus, or families with infantile esotropia or nystagmus. By comparing affected and unaffected relatives, they hope to identify shared genetic changes. The study is observational and does not test any treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could identify genes that cause strabismus and nystagmus, pointing toward future genetic tests or therapies.
What could go wrong: This is an observational study, not a treatment trial. Finding genetic links does not guarantee new treatments, and results may take years to apply.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NYSTAGMUS, CONGENITAL are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

congenital nystagmus esotropia exotropia pathologic nystagmus strabismus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NYSTAGMUS, CONGENITAL STRABISMUS

Contacts and locations

Locations

Boston Children's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.