Your genes may predict your risk of a torn rotator cuff

NCT ID NCT04831164

Recruiting now Knowledge-focused Sponsor: University of Michigan Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is collecting DNA and MRI data from 3,500 adults aged 40 to 85 to find genetic variations linked to rotator cuff tears. Researchers will compare people with and without tears to identify risk genes. The goal is to better understand why tears happen and why some treatments work better for certain people.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help identify people at higher risk for rotator cuff tears and guide more personalized treatment plans.
What could go wrong: This is an observational genetic study, not a treatment trial. It may not lead to direct medical changes, and results may take years to apply.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Rotator Cuff Injuries rotator cuff syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ROTATOR CUFF TEARS

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Beth Israel Deaconess Medical Center
COMPLETED

Boston, Massachusetts, 02215, United States
Boston Medical Center
COMPLETED

Boston, Massachusetts, 02118, United States
Brigham and Women's Hospital
COMPLETED

Boston, Massachusetts, 02115, United States
Ohio State University
NOT_YET_RECRUITING

Columbus, Ohio, 43202, United States

Contact
Orthopedic Institute
COMPLETED

Sioux Falls, South Dakota, 57117, United States
Parkland Health and Hospital System
COMPLETED

Dallas, Texas, 75390, United States
University of Iowa
RECRUITING

Iowa City, Iowa, 52242, United States

Contact Email: •••••@•••••
University of Michigan
RECRUITING

Ann Arbor, Michigan, 48108, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Texas Southwestern Medical Center
RECRUITING

Dallas, Texas, 75390, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Vanderbilt University Medical Center
COMPLETED

Nashville, Tennessee, 37232, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.