Gene hunt aims to prevent infections after hip and knee surgery

NCT ID NCT05159739

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: University of Utah Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is looking for genes that might make some people more likely to get an infection after hip or knee replacement surgery. Researchers will collect blood or saliva samples from 150 people in families with a history of such infections, plus unaffected relatives. The goal is to find genetic clues that could one day help doctors personalize care to lower infection risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to personalized care plans to reduce infection risk after joint replacement surgery.

What could go wrong

This is an observational study, not a treatment trial. It only looks for genetic links and may not find clear or actionable results.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

inherited disease susceptibility periprosthetic joint infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Utah Orthopaedic Center

    Salt Lake City, Utah, 84108, United States