Gene therapy trial aims to halt vision loss in rare inherited eye disease

NCT ID NCT05926583

Summary

This study is testing a gene therapy called AAV5-hRKp.RPGR to see if it is safe and can help preserve or improve vision in Japanese patients with a specific, inherited form of retinitis pigmentosa (XLRP). The therapy involves a one-time injection into the back of both eyes to deliver a working copy of a faulty gene (RPGR) that causes the disease. The main goal is to check for side effects, while also measuring changes in vision over 52 weeks.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Hospital Organization Tokyo Medical Center

    RECRUITING

    Meguro-ku, 1528902, Japan

Conditions

Explore the condition pages connected to this study.