New gene therapy aims to restore saliva in cancer survivors

NCT ID NCT02446249

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a gene therapy designed to help people with dry mouth after radiation for head and neck cancer. The treatment delivers a gene into one saliva gland to help it produce more saliva. The trial includes 17 adults and focuses on safety, with follow-up over three years.

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Conditions

The condition(s) this trial relates to.

Head and Neck Neoplasms head and neck squamous cell carcinoma Xerostomia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center, 9000 Rockville Pike

    Bethesda, Maryland, 20892, United States