Gene therapy for diabetic foot ulcers fails to reach finish line

NCT ID NCT02563522

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a gene therapy called VM202 to help heal chronic foot ulcers in people with diabetes and poor leg circulation. The treatment was given as injections into the calf muscle. The study was stopped early after enrolling only 44 participants, so results are limited.

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Conditions

The condition(s) this trial relates to.

Diabetic Foot Foot Ulcer peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Acclaim Bone & Joint Institute

    Fort Worth, Texas, 76107, United States

  • Advanced Foot & Ankle Center

    Las Vegas, Nevada, 89119, United States

  • Arizona Research Center

    Phoenix, Arizona, 85053, United States

  • Bay Area Foot and Ankle

    Castro Valley, California, 94546, United States

  • Center for Clinical Research Inc.

    San Francisco, California, 94115, United States

  • Central Research Associates, Inc.

    Birmingham, Alabama, 35205, United States

  • Foot and Ankle Clinic

    Los Angeles, California, 90057, United States

  • Futuro Clinical Trials

    McAllen, Texas, 78501, United States

  • LCC Medical Research Institute

    Miami, Florida, 33126, United States

  • MedResearch, Inc

    El Paso, Texas, 79932, United States

  • Miami Dade Medical Research Institute, LLC

    Miami, Florida, 33176, United States

  • NEA Baptist

    Jonesboro, Arkansas, 72401, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Olive View-UCLA Education & Research Institute

    Sylmar, California, 91342, United States

  • Oregon Foot and Ankle Center

    Eugene, Oregon, 97401, United States

  • Sacramento Foot and Ankle

    Carmichael, California, 95608, United States

  • Saint Louis University

    St Louis, Missouri, 63110, United States

  • Texas Heart Institute

    Houston, Texas, 77030, United States

  • UMASS Memorial Med Center

    Worcester, Massachusetts, 01655, United States

  • USC Keck School of Medicine

    Los Angeles, California, 90033, United States

  • University of Arizona

    Tucson, Arizona, 85724, United States

  • VA Long Beach Healthcare System

    Long Beach, California, 90822, United States