Could a single gene therapy injection slow Alzheimer's?

NCT ID NCT05040217

First seen Oct 31, 2025 · Last updated May 02, 2026 · Updated 22 times

Summary

This early-stage study tests a gene therapy that delivers a protein called BDNF directly into the brain. The goal is to see if it is safe and can slow or prevent brain cell loss in people with early Alzheimer's disease or mild cognitive impairment. The study involves 12 participants and uses a harmless virus to help brain cells produce the protective protein.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Ohio State University

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California - San Diego

    RECRUITING

    La Jolla, California, 92093, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.