Experimental cancer drug GEN1078 tested in just 3 people – trial halted early

NCT ID NCT06771921

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tested an experimental drug called GEN1078 in 3 people with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check for side effects and see how the body processes the drug. The trial was terminated early, so results are very limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

GEN1078 (an experimental drug)

What this could lead to

If it works, this could point toward a new treatment option for advanced solid tumors that have not responded to other therapies.

What could go wrong

This trial was terminated early with only 3 participants, so we have very little data. It is too early to know if GEN1078 is safe or effective, and many early cancer drugs fail to show benefit.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centro Integral Oncologico Clara Campal

    Madrid, Spain

  • Clinica Universidad de Navarra

    Pamplona, Spain

  • Hospital Universitari Vall d'Hebron

    Barcelona, Spain

  • Hospital Universitary Fundacion Jimenez Diaz

    Madrid, Spain

  • NEXT Oncology Madrid

    Madrid, Spain

  • Righshospitalet (Copenhagen University Hospital)

    Copenhagen, Denmark