New study tests program to boost daily function in older cancer survivors

NCT ID NCT05006482

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests whether a program called GEM-S (geriatric evaluation and management with survivorship health education) can improve physical function in older cancer survivors. About 668 participants who have completed chemotherapy for lymphoma or solid tumors will be randomly assigned to GEM-S or usual care. The program includes a geriatric assessment, tailored health advice, and exercise sessions, aiming to help survivors maintain their ability to perform daily activities and improve mental well-being.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Geriatric evaluation and management plus survivorship health education (GEM-S)
What this could lead to
If successful, this could lead to a standard program that helps older cancer survivors maintain their physical abilities, mental sharpness, and quality of life after chemotherapy.
What could go wrong
This is a large phase 3 trial, but the intervention is complex and may not work better than usual care. Results depend on how well participants follow the program, and benefits may vary widely.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chesapeake Regional Medical Center

    RECRUITING

    Chesapeake, Virginia, 23320, United States

    Contact

    Contact Email: •••••@•••••

  • Community Medical Center

    RECRUITING

    Scranton, Pennsylvania, 18510, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fairview Southdale Hospital

    RECRUITING

    Edina, Minnesota, 55435, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Geisinger Cancer Center Dickson City

    RECRUITING

    Dickson City, Pennsylvania, 18519, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Geisinger Medical Center

    RECRUITING

    Danville, Pennsylvania, 17822, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Geisinger Wyoming Valley/Henry Cancer Center

    RECRUITING

    Wilkes-Barre, Pennsylvania, 18711, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • HSHS Sacred Heart Hospital

    SUSPENDED

    Eau Claire, Wisconsin, 54701, United States

  • Hawaii Cancer Care - Westridge

    RECRUITING

    ‘Aiea, Hawaii, 96701, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hawaii Cancer Care Inc - Waterfront Plaza

    RECRUITING

    Honolulu, Hawaii, 96813, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Helen F Graham Cancer Center

    RECRUITING

    Newark, Delaware, 19713, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hennepin County Medical Center

    RECRUITING

    Minneapolis, Minnesota, 55415, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Highland Hospital

    RECRUITING

    Rochester, New York, 14620, United States

    Contact

    Contact Phone: •••-•••-••••

  • Kaiser Permanente-Fremont

    RECRUITING

    Fremont, California, 94538, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kaiser Permanente-San Francisco

    RECRUITING

    San Francisco, California, 94115, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kapiolani Medical Center for Women and Children

    RECRUITING

    Honolulu, Hawaii, 96826, United States

    Contact Phone: •••-•••-••••

    Contact

  • Lake Regional Hospital

    RECRUITING

    Osage Beach, Missouri, 65065, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Lakeview Hospital

    RECRUITING

    Stillwater, Minnesota, 55082, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Lewis and Faye Manderson Cancer Center

    RECRUITING

    Tuscaloosa, Alabama, 35401, United States

    Contact

    Contact Phone: •••-•••-••••

  • Marshfield Medical Center - Weston

    RECRUITING

    Weston, Wisconsin, 54476, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Marshfield Medical Center-River Region at Stevens Point

    RECRUITING

    Stevens Point, Wisconsin, 54482, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medical Oncology Hematology Consultants PA

    RECRUITING

    Newark, Delaware, 19713, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Minnesota Oncology Hematology PA-Woodbury

    RECRUITING

    Woodbury, Minnesota, 55125, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Monticello Cancer Center

    RECRUITING

    Monticello, Minnesota, 55362, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Northwell Health/Center for Advanced Medicine

    RECRUITING

    Lake Success, New York, 11042, United States

    Contact

    Contact Phone: •••-•••-••••

  • Novant Health Breast Surgery - Greensboro

    RECRUITING

    Greensboro, North Carolina, 27403, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Novant Health Cancer Institute - Kernersville

    RECRUITING

    Kernersville, North Carolina, 27284, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Novant Health Cancer Institute - Mount Airy

    RECRUITING

    Mount Airy, North Carolina, 27030, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Novant Health Cancer Institute - Statesville

    RECRUITING

    Stateville, North Carolina, 28625, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Novant Health Cancer Institute - Thomasville

    RECRUITING

    Thomasville, North Carolina, 27360, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Novant Health Forsyth Medical Center

    RECRUITING

    Winston-Salem, North Carolina, 27103, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Noyes Memorial Hospital/Myers Cancer Center

    RECRUITING

    Dansville, New York, 14437, United States

    Contact

    Contact Email: •••••@•••••

  • OSF Saint Anthony's Health Center

    RECRUITING

    Alton, Illinois, 62002, United States

    Contact

    Contact Phone: •••-•••-••••

  • Pali Momi Medical Center

    RECRUITING

    ‘Aiea, Hawaii, 96701, United States

    Contact Phone: •••-•••-••••

    Contact

  • Park Nicollet Clinic - Saint Louis Park

    RECRUITING

    Saint Louis Park, Minnesota, 55416, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Pluta Cancer Center

    RECRUITING

    Rochester, New York, 14623, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Regions Hospital

    RECRUITING

    Saint Paul, Minnesota, 55101, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rice Memorial Hospital

    RECRUITING

    Willmar, Minnesota, 56201, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Saint Vincent Hospital Cancer Center Green Bay

    RECRUITING

    Green Bay, Wisconsin, 54301, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Saint Vincent Hospital Cancer Center at Saint Mary's

    RECRUITING

    Green Bay, Wisconsin, 54303, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • South Central Medical and Resource Center

    RECRUITING

    Lindsay, Oklahoma, 73052, United States

    Contact Phone: •••-•••-••••

    Contact

  • Straub Clinic and Hospital

    RECRUITING

    Honolulu, Hawaii, 96813, United States

    Contact Phone: •••-•••-••••

    Contact

  • ThedaCare Regional Cancer Center

    RECRUITING

    Appleton, Wisconsin, 54911, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tripler Army Medical Center

    RECRUITING

    Honolulu, Hawaii, 96859, United States

    Contact

    Contact Phone: •••-•••-••••

  • University of Rochester

    RECRUITING

    Rochester, New York, 14642, United States

    Contact

    Contact Phone: •••-•••-••••

  • Wilmot Cancer Institute at Webster

    RECRUITING

    Webster, New York, 14580, United States

    Contact

    Contact Email: •••••@•••••

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