Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can a gel tame swollen gums better than another?

NCT ID NCT07776197

Disease control Sponsor: H.P. Government Dental College and Hospital Shimla Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 20, 2026 · Last updated Aug 21, 2026 · Updated 1 time

Summary

This trial tests whether adding a medicated gel to standard deep cleaning helps reduce gum inflammation more than cleaning alone. About 120 adults with plaque-induced gingivitis will use either a chlorhexidine gel, a chlorhexidine-plus-metronidazole gel, or a placebo gel twice daily for six weeks. Researchers will measure changes in plaque, gum inflammation, and pocket depths over 12 weeks to see which approach works best.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Topical gels containing chlorhexidine gluconate alone or combined with metronidazole, applied to the gums after brushing.
What this could lead to
If one gel proves superior, it could point to a more effective at-home add-on to professional dental cleaning for managing gum inflammation.
What could go wrong
The trial is relatively small and short-term, and results may not apply to more severe gum disease. Gels may cause temporary taste changes or staining.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

120 people

The number who actually took part.

Started

May 2025

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients aged between 18- 50 years. 2. Patients with at least \>20 teeth. 3. Patients with gingivitis and stage-1 grade A periodontitis. 4. Patients with clinical criteria of gingival index ≥ 1 (Loe and Silness). 5. Systematically healthy patient with no co-morbidities. 6. History of no active periodontal treatment in the last 6 months. Exclusion Criteria: 1. History of smoking or use of smokeless tobacco. 2. Pregnant or lactating females. 3. Subjects with removal or fixed dental prosthesis and undergoing orthodontic treatment. 4. Use of antibiotics in the last 30 days. 5. Subjects with hematological disorders, immunocompromised and any other systemic illnesses. 6. History of chronic alcoholism. 7. Allergic to Metronidazole or Chlorhexidine. 8. Patients on medications that have effects on gingival enlargements.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Plaque induced gingivitis are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

gingivitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Plaque induced gingivitis

Contacts and locations

Locations

  • Government Dental College and Hospital, Shimla

    Shimla, Himachal Pradesh, 171001, India

More trials for these conditions

Other studies related to the condition(s) this trial covers.