Engineered immune cells take aim at two cancer targets

NCT ID NCT05437328

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new treatment using a patient's own immune cells, engineered to recognize and attack cancer cells that have two specific markers (GD2 and CD56). The trial includes 60 people with advanced cancers that have not responded to standard therapy. The goal is to see if this approach is safe and effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bi-4SCAR GD2/CD56 T cells

What this could lead to

If successful, this could offer a new treatment option for patients with certain hard-to-treat cancers that express GD2 or CD56.

What could go wrong

This is an early-phase trial with only 60 participants, so results may not apply broadly. CAR-T therapy can cause serious side effects like cytokine release syndrome.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shenzhen Geno-immune Medical Institute

    RECRUITING

    Shenzhen, Guangdong, 518000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••