Scientists probe why gastric bypass causes dangerous blood sugar drops
NCT ID NCT00992901
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study looks at how gastric bypass surgery affects insulin and blood sugar control, focusing on gut hormones and nerve signals. Researchers will compare three groups: people who had the surgery and now have severe low blood sugar, those who had the surgery without symptoms, and healthy volunteers without surgery. Participants receive short-acting drugs to measure how their bodies respond, helping explain why some develop life-threatening hypoglycemia years after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Exendin-(9-39), Atropine, GLP-1 and GIP
What this could lead to
If successful, this could clarify why some people develop dangerous low blood sugar after gastric bypass, pointing toward better prevention or treatment.
What could go wrong
This is an early-phase observational study, not testing a new treatment. Results may not lead to direct therapies, and findings may not apply to all patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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South Texas Veterans Health Care System
RECRUITINGSan Antonio, Texas, 78229, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Texas Diabetes Institute - University Health System
RECRUITINGSan Antonio, Texas, 78207, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••