Mushroom powder may lift mood in thyroid cancer survivors

NCT ID NCT07524777

Recruiting now Symptom relief Sponsor: Ling Zhiqiang Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a mushroom supplement called Ganoderma lucidum spore powder can reduce depression in women who have had thyroid cancer surgery. Three hundred participants will take either the supplement or a placebo daily for three months. Researchers will measure changes in mood, sleep, and gut bacteria to see if the supplement works through the gut-brain connection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Sporoderm-removed Ganoderma lucidum spore powder (a mushroom supplement)
What this could lead to: If it works, this could offer a natural way to improve mood and sleep in thyroid cancer survivors with depression.
What could go wrong: This is an early-stage trial with no prior proof in this group. The supplement may not outperform placebo, and results may not apply to men or other ethnicities.

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Conditions

The condition(s) this trial relates to.

Depression depressive disorder thyroid cancer thyroid gland papillary carcinoma Thyroid Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION THYROID CANCER

Contacts and locations

Locations

Zhejiang Cancer Hospital
RECRUITING

Hangzhou, Zhejiang, 310022, China

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