Cancer drug trial halted early – what happened?
NCT ID NCT04189445
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial tested the drug futibatinib in 115 people with advanced solid tumors or blood cancers that have specific FGFR gene changes. The goal was to see if the drug could shrink tumors or cause remission. The study was terminated early, so final results are not yet clear.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Futibatinib (a targeted cancer drug taken as a daily pill)
What this could lead to
If successful, futibatinib could offer a new treatment option for certain cancers driven by FGFR gene changes.
What could go wrong
This trial was terminated early, so data is limited. The drug may not work for all FGFR-related cancers, and side effects are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Acibadem Adana Hospital
Adana, 01130, Turkey (Türkiye)
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Acibadem Maslak Hospital
Istanbul, 34457, Turkey (Türkiye)
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Aichi Cancer Center Hospital
Nagoya, Aichi-ken, 464-8681, Japan
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Akademiska Sjukhuset
Uppsala, 75185, Sweden
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Antoni van Leeuwenhoek
Amsterdam, 1066 CX, Netherlands
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Asan Medical Center
Seoul, 05505, South Korea
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Azienda Ospedaliera Universitaria Careggi
Florence, 50134, Italy
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Azienda Ospedaliera Universitaria Integrata Verona (Ospedale Borgo Trento)
Verona, 37124, Italy
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Banner MD Anderson Cancer Center
Gilbert, Arizona, 85234-2165, United States
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215-5400, United States
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Centre Antoine Lacassagne
Nice, Alpes Maritimes, 06200, France
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Centre Georges François Leclerc
Dijon, Côte-d'Or, 21079, France
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Centre Hospitalier Lyon Sud
Pierre-Bénite, Rhone, 69495, France
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Centre Léon Bérard
Lyon, Rhone, 69008, France
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Centre Paul Strauss
Strasbourg, Bas Rhin, 67000, France
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Centro Hospitalar de Lisboa Central, E.P.E. - Hospital de Santo António dos Capuchos
Lisbon, 1169-050, Portugal
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Centro Hospitalar do Porto, E.P.E - Hospital de Santo Antonio
Porto, 4099-001, Portugal
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Clinica Universidad de Navarra
Pamplona, 31008, Spain
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Erasmus Medisch Centrum
Rotterdam, 3015 AA, Netherlands
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Fox Chase Cancer Center
Philadelphia, Pennsylvania, 53705, United States
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Fundação Champalimaud
Lisbon, 4099-001, Portugal
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Georgetown University - Lombardi Comprehensive Cancer Center
Washington D.C., District of Columbia, 20007, United States
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Henry Ford Hospital
Woodhaven, Michigan, 48183, United States
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Hokkaido University Hospital
Sapporo, Hokkaido, 060-8648, Japan
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Hong Kong United Oncology Centre
Jordon, 0000, Hong Kong
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Hospital Clinico Universitario de Valencia
Valencia, 46010, Spain
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Hospital Universitari Vall d'Hebron
Barcelona, 08035, Spain
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Hospital Universitari i Politecnic La Fe
Valencia, 46026, Spain
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Hospital Universitario HM Madrid Sanchinarro
Madrid, 28050, Spain
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Hospital Universitario Ramon y Cajal
Madrid, 28034, Spain
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Hospital Universitario Virgen Macarena
Seville, 41009, Spain
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Houston Methodist Cancer Center
Houston, Texas, 77030, United States
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Hôpital Saint-Louis
Paris, Paris, 75475, France
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IEO Istituto Europeo di Oncologia
Milan, 20141, Italy
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Institut Bergonié
Bordeaux, Gironde, 33076, France
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Institut Gustave Roussy
Villejuif, Val De Marne, 94805, France
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Institut Jules Bordet
Brussels, 1000, Belgium
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Instituto Valenciano de Oncologia IVO
Valencia, 46009, Spain
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Istituto Scientifico Romagnolo Per Lo Studio e La Cura Dei Tumori
Meldola, Forli - Cesena, 47014, Italy
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Karolinska universitetssjukhuset - Solna
Solna, 171 64, Sweden
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Mercy Clinic Oncology and Hematology - Coletta
Oklahoma City, Oklahoma, 73120, United States
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NHO Shikoku Cancer Center
Matsuyama, Ehime, 791-0280, Japan
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Namik Kemal University
Tekirdağ, 59100, Turkey (Türkiye)
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National Cancer Center Hospital
Chūōku, Tokyo-To, 104-0045, Japan
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National Cancer Center Hospital East
Kashiwa-shi, Chiba, 277-8577, Japan
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National University Cancer Institute
Singapore, 119074, Singapore
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Osaka University Hospital
Suita-shi, Osaka, 565-0871, Japan
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Ospedale Sacro Cuore Don Calabria
Negrar, Verona, 37024, Italy
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Samsung Medical Center
Seoul, 06351, South Korea
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Sarah Cannon Research Institute UK
London, Greater London, W1G 6AD, United Kingdom
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Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, 13620, South Korea
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Seoul National University Hospital
Seoul, 03080, South Korea
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Severance Hospital, Yonsei University Health System
Seoul, 03722, South Korea
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The University of Hong Kong
Hong Kong, Hong Kong
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The University of Texas M. D. Anderson Cancer Center
Houston, Texas, 77030, United States
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UCLA Medical Center
Los Angeles, California, 90404, United States
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Universitaetsklinikum Freiburg
Freiburg im Breisgau, Baden-Wurttemberg, 79106, Germany
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Universitaetsklinikum Heidelberg
Heidelberg, Baden-Wurttemberg, 69120, Germany
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Universitaetsklinikum Koeln
Cologne, North Rhine-Westphalia, 50924, Germany
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University of Chicago Comprehensive Cancer Center
Chicago, Illinois, 60637, United States
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University of Maryland
Baltimore, Maryland, 21201, United States