New triple therapy targets hard-to-treat lung cancer before surgery
NCT ID NCT07492342
First seen Apr 07, 2026 · Last updated May 09, 2026 · Updated 3 times
Summary
This study tests a new approach for people with a certain genetic lung cancer (KRAS G12C mutation) that can be removed with surgery. Before surgery, patients receive a targeted pill (fulzerasib) for 6 weeks, then a 2-week break, followed by 3 cycles of immunotherapy (sintilimab) plus standard chemotherapy. The goal is to see if this combination can shrink or eliminate the tumor before surgery, potentially improving long-term outcomes. About 30 adults with stage IB to IIIA non-small cell lung cancer will participate.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Peking Union Medical College Hospital
NOT_YET_RECRUITINGBeijing, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Guangzhou Medical University
RECRUITINGGuangzhou, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Zhejiang University School of Medicine
NOT_YET_RECRUITINGZhejiang, China
Contact
Conditions
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