New CAR t combo takes on Hard-to-Treat myeloma

NCT ID NCT07221032

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests a new type of CAR T-cell therapy called FT836, given together with the drug daratumumab, in 12 adults with multiple myeloma that has come back or stopped responding to at least three prior treatments. The main goal is to see if the combination is safe and to find the best dose. Participants receive FT836 cells by IV and daratumumab by IV.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

FT836 CAR T-cells and daratumumab (Darzalex)

What this could lead to

If it works, this could point toward a new combination treatment for multiple myeloma that has stopped responding to other therapies.

What could go wrong

This is a very early, small phase 1 trial with only 12 participants. It is designed mainly to check safety and find the right dose, not to prove effectiveness. Side effects like cytokine release syndrome are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for REFRACTORY MULTIPLE MYELOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

plasma cell myeloma refractory plasma cell neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Froedtert & the Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••