New drug combo could improve treatment for Hard-to-Treat colorectal cancer

NCT ID NCT07362836

First seen Feb 01, 2026 · Last updated May 15, 2026 · Updated 12 times

Summary

This phase 3 trial tests whether a new drug, fruquintinib, combined with chemotherapy works better than the standard treatment (bevacizumab plus chemo) for people with a specific type of advanced colorectal cancer (RAS-mutant). About 224 adults aged 18-75 with metastatic disease that has worsened after first-line therapy will be randomly assigned to one of the two treatments. The main goal is to see how long patients live without their cancer growing.

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