Can a simple injection ease frozen shoulder pain?

NCT ID NCT05983081

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether injecting hyaluronic acid into the shoulder joint could help people with frozen shoulder. 46 participants received either the injections plus physical therapy or physical therapy alone. Researchers measured shoulder movement and disability over 26 weeks to see if the injections provided extra benefit.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
hyaluronic acid
What this could lead to
If effective, this could offer a non-surgical option to improve shoulder movement and reduce disability in people with frozen shoulder.
What could go wrong
This is a small, single-center trial with only 46 participants. Results may not apply to everyone, and the effect may be modest or no better than physical therapy alone.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Tri-Service General Hospital

    Taipei, Alberta, 114, Taiwan

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Other studies related to the condition(s) this trial covers.