New drug combo shows promise in Hard-to-Treat cancers
NCT ID NCT03875820
First seen Mar 20, 2026 · Last updated Jun 13, 2026 · Updated 12 times
Summary
This early-phase trial tests two experimental drugs, defactinib and VS-6766, together in people with advanced solid tumors that have stopped responding to standard treatments. The study includes patients with certain lung, ovarian, endometrial, and pancreatic cancers. The main goals are to find the safest dose and to check how well the combination controls the disease.
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This is a summary of
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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The Christie NHS Foundation Trust
Manchester, Greater Manchester, M20 4BX, United Kingdom
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The Newcastle Upon Tyne Hospitals NHS Foundation Trust - Freeman Hospital
Newcastle, NE7 7DN, United Kingdom
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The Royal Marsden NHS Foundation Trust
Sutton, Surrey, SM2 5PT, United Kingdom
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The Royal Marsden NHS Foundation Trust - Gynecology Unit
London, SW3 6JJ, United Kingdom
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The Royal Marsden NHS Foundation Trust - Gynecology Unit
Sutton, SM2 5PT, United Kingdom
Conditions
Explore the condition pages connected to this study.