Heated chemo inside the abdomen may boost colon cancer survival

NCT ID NCT06783491

First seen Nov 01, 2025 · Last updated Apr 26, 2026 · Updated 22 times

Summary

This study tests whether giving chemotherapy before surgery, with or without heated chemotherapy directly into the abdomen (HIPEC), can help people with locally advanced colon cancer live longer without the cancer coming back. About 1,083 adults aged 18–75 with stage T4 or high-risk T3 colon cancer will be randomly assigned to one of three groups: standard treatment (surgery then chemo), chemo before surgery plus HIPEC, or chemo before surgery alone. The main goal is to see if the new approaches increase the number of patients who remain cancer-free three years after treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LOCALLY ADVANCED COLORECTAL CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital Universitario Reina Sofia

    Córdoba, Córdoba, 14004, Spain

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.