Could a vitamin help kids with autism? new trial tests folinic acid

NCT ID NCT07630506

Recruiting now Symptom relief Sponsor: KK Women's and Children's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether folinic acid, a form of vitamin B9, can improve autism symptoms in children aged 3 to 10. About 184 children will receive either folinic acid or a placebo for 12 weeks, then all can try the vitamin. The goal is to see if it reduces behavioral and communication challenges.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: folinic acid (a form of vitamin B9)
What this could lead to: If it works, this could point toward a safe, vitamin-based option to ease autism symptoms in children.
What could go wrong: This is an early Phase 2 trial with only 184 children, so results may not be conclusive. Folinic acid is generally safe but may not improve symptoms for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

autism spectrum disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTISM SPECTRUM DISORDER

Contacts and locations

Locations

KK Women's and Children's Hospital
RECRUITING

Singapore, Singapore, Singapore

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