Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can chemo before surgery clear rectal cancer and liver tumors?

NCT ID NCT07467434

Recruiting now Disease control Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether giving FOLFIRINOX chemotherapy before surgery helps people with mid or lower rectal cancer that has spread to the liver. The goal is to see if both the rectal tumor and liver spots can be completely removed. About 550 adults will take part, and the main result is the rate of complete removal at 18 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
FOLFIRINOX chemotherapy
What this could lead to
If successful, this could show that giving FOLFIRINOX before surgery helps more patients have all their cancer removed completely, potentially improving long-term survival.
What could go wrong
This is an observational study, not a randomized trial, so it cannot prove FOLFIRINOX is better than other approaches. Results may not apply to all patients, and chemotherapy has side effects like fatigue, nausea, and nerve damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

rectal cancer rectal neoplasm rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS RECTAL CANCER SURGICAL THERAPY SYNCHRONOUS LIVER METASTASES

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Digestive Surgery Department, Bicêtre University Hospital AP-HP

    RECRUITING

    Le Kremlin-Bicêtre, 94270, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

More trials for these conditions

Other studies related to the condition(s) this trial covers.